题  目：Molecular Structures of Polymer and Biological Molecules at Interfaces

报告人：Prof. Zhan Chen, University of Michigan, USA

时  间：2016年4月27日（星期三），下午14:30

地  点：南楼2层会议室

邀请人：裘晓辉研究员（Tel：82545583）

摘要：

It is important to study molecular structures of polymer molecules and biological molecules at interfaces because such structures control many interfacial properties such as adhesion, biocompatibility, biofouling, membrane protein function, and antimicrobial activity. However, it is difficult to probe buried interfaces such as solid/liquid and solid/solid interfaces in situ nondestructively. We have successfully applied a nonlinear optical laser technique, sum frequency generation (SFG) vibrational spectroscopy, to elucidate molecular structures of buried polymer/metal and polymer/polymer interfaces in situ, and to correlate structures to interfacial properties. We also developed systematic means to reveal molecular structures of peptides and proteins associated with cell membranes, as well as surface immobilized antimicrobial peptides and enzymes at solid/liquid interfaces. In addition, we successfully probed molecular interactions between model cell membranes and different materials including nanoparticles. We demonstrated that SFG is a powerful tool to investigate molecular structures of complex interfaces in situ in real time.

报告人简介：

Professor Zhan Chen received his BS, MS and PhD degrees from Peking University, Institute of Physics of Chinese Academy of Sciences (with Prof. Jingkui Liang), and University of California at Berkeley (with Prof. Herbert Strauss) respectively.  He did his postdoctoral research in Lawrence Berkeley National Laboratory (with Prof. Gabor Somorjai). Currently he is a professor of chemistry, macromolecular science and engineering, biophysics, and applied physics at the University of Michigan. Professor Chen’s research is focused on the molecular level understanding of structures of polymers and biological molecules at interfaces using nonlinear optical spectroscopic techniques. He has published more than 200 journal articles and has presented more than 250 invited talks.